产品货号:
Z28827
中文名称:
TRIM25抗体
英文名称:
Anti-TRIM25 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-TRIM25 Antibody |
指标别名 | EFP;RING finger protein 147;RNF147;TRIM25;tripartite motif containing 25;Z147;Zinc finger protein 147;ZNF147 |
克隆性 | Polyclonal |
检验物种 | human,mouse |
应用范围 | ELISA,WB,ICC,IF |
基因名称 | TRIM25 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | TRIM25 antibody was raised against a 19 amino acid synthetic peptide from near the carboxy terminus of human TRIM25.The immunogen is located within amino acids 520 - 570 of TRIM25. |
计算分子量 | 71kDa |
成分 | TRIM25 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | TRIM25 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | TRIM25,also known as estrogen responsive finger protein (EFP) is a member of the RING finger-B box-coiled coil family and is a downstream target of estrogen receptor a.Mice lacking this gene displayed an underdeveloped uterus and reduced estrogen responsiveness demonstrating that this protein is essential for estrogen dependent proliferation.TRIM25 expression is increased in breast carcinoma where it promotes the growth of breast tumor by functioning as an E3 ubiquitin ligase that targets the negative cell cycle checkpoint 14-3-3s.Recent reports have indicated that TRIM25 E3 ubiquitin ligase is essential for the retinoic-acid-inducible gene 1 (RIG-1) signaling pathway to elicit host antiviral innate immunity. |
Uniprot ID | Q14258 |
基因名全称 | Tripartite motif-containing 25 |
蛋白名全称 | Tripartite motif-containing 25 |
推荐稀释比 | TRIM25 antibody can be used for detection of TRIM25 by Western blot at 1μg/mL.Antibody can also be used for immunocytochemistry starting at 20μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunocytochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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